Drosophila brain tumor metastases express both neuronal and glial cell type markers
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چکیده
منابع مشابه
Drosophila brain tumor metastases express both neuronal and glial cell type markers.
Loss of either lgl or brat gene activity in Drosophila larvae causes neoplastic brain tumors. Fragments of tumorous brains from either mutant transplanted into adult hosts over-proliferate, and kill their hosts within 2 weeks. We developed an in vivo assay for the metastatic potential of tumor cells by quantifying micrometastasis formation within the ovarioles of adult hosts after transplantati...
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us&y a cellular neurobiologist struggles to link findings made in simple cellular systems to the problems of the neuron. It is therefore gratifying when the flow is reversed and discoveries in neurons are seminal to the understanding of cell biology in general. This has been especially true for the past year in the field of membrane traffic in the nerve terminal. As reviewed by Martin (pp 626-6...
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Kang Shen is an investigator in the Howard Hughes Medical Institute and an associate professor in the Department of Biology at Stanford University. His laboratory studies synapse formation in C. elegans and mammals with a focus on synaptic target recognition, presynaptic assembly, and axonal transport. Introduction The wiring of the nervous system is arguably the most challenging question in de...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2007
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2006.09.019